Editorial: Highlights in Alzheimer's and Parkinson's disease

Magnesium and Alzheimers Disease: The Cholinergic Hypothesis

The cholinergic deficit in Alzheimer’s disease (AD) remains the cornerstone for the understanding of chemical signal transfer. Hypofunctions of cholinergic systems are significantly involved in the signs and symptoms of senile dementia of the Alzheimer type. Cognitive deficits in AD have been widely associated with dysfunction of the cholinergic system. As a diagnostic marker of AD the activity...

Editorial: Highlights of a Year in AIDS

Here are my choices for key achievements and discoveries in HIV/AIDS, from those which heralded the new year 2006 through the most recent findings in early 2007. Several are updates of reports first mentioned in my editorials over the past year. MALE CIRCUMCISION Three randomized controlled interventions conducted in Africa among general populations of uncircumcised men found that circumcision ...

Editorial: “Disease-Only” alleles and genotypes in complex disorders?

Glucose Role in Treatment of Alzheimers’ Disease

1. Dong H, Csernansky JG (2009) Effects of Stress and Stress Hormones on Amyloidβ Protein and Plaque Deposition. J Alzheimers Dis 18: 459-469. 2. Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, et al. (2006) Plasma cortisol and progression of dementia in subjects with Alzheimer‐ type dementia. Am J Psychiatry 163: 2164-2169. 3. Swaab DF, Raadsheer FC, Endert E, Hofman MA, Kamphorst W, et al. ...

Current State of Alzheimers Disease Research Therapeutics

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